FEN-1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation The PAK proteins are a

The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins

The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains

Adapter protein that links FGR and NGF receptors to downstream signaling pathways

the rate-limiting step in cholesterol synthesis

The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage

FEN-1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation The PAK proteins are aFlap endonuclease 1 encoded by FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG RAD2 endonuclease family and is