SREBP-1 (Acetyl-Lys324) Polyclonal Antibody, 100ul Pipette Filler The N-terminal propeptide contains thrombospondin

The N-terminal propeptide contains thrombospondin N-terminal-like and laminin G-like domains

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The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho| a protein involved in neurogenesis during embryonic development

Two alternatively spliced transcript variants have been found

Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections

SREBP-1 (Acetyl-Lys324) Polyclonal Antibody, 100ul Pipette Filler The N-terminal propeptide contains thrombospondinThis gene encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols