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Nephrin Polyclonal Antibody, 100ul Tubes Ena-VASP family members contain an

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Nephrin Polyclonal Antibody, 100ul Tubes Ena-VASP family members contain anNPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. NPHS1 is primarily expressed in renal tissues, and the protein is a type 1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this

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Description

Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions

Also found in early endosomes in the somatodendritic region

This gene is expressed with transcripts of 6

The protein is thought to be involved in cell motility| phagocytosis| membrane trafficking and mitogenesis

Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160)

Nephrin Polyclonal Antibody, 100ul Tubes Ena-VASP family members contain anNPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. NPHS1 is primarily expressed in renal tissues, and the protein is a type 1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this

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