Parkin Polyclonal Antibody, 100ul Cell Culture Flasks Mutations in this gene are

Mutations in this gene are associated with visceral heterotaxy-6

This gene belongs to the peroxin-12 family

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mostly in undifferentiated peripheral sebocytes

Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1)

Parkin Polyclonal Antibody, 100ul Cell Culture Flasks Mutations in this gene areThe precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of PARK2 produces multiple transcript variants encoding distinct isoforms. Additional splice variants of PARK2 have