Dynactin 2 Polyclonal Antibody, 100ul Electronic Pipette Inhibits HSPA8/HSC70 ATPase and chaperone

Inhibits HSPA8/HSC70 ATPase and chaperone activities Diseases associated with HSPH1 include hepatitis d

and seminiferous tubules

It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs)

subcellular location:Localization to the cytoplasm or to the cell membrane is developmentally and ontogenetically regulated

and its alternative splicing generates 3 transcript variants

Dynactin 2 Polyclonal Antibody, 100ul Electronic Pipette Inhibits HSPA8/HSC70 ATPase and chaperoneDCTN2 encodes a 50 kD subunit of dynactin, a macromolecular complex consisting of 10 11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER to Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4 5 copies per