Microcephalin Polyclonal Antibody, 100ul Mammalian Expression Ran is active in its

Ran is active in its GTP-bound form and inactive in its GDP-bound form

This member is identified as a 'silent subunit'

Designed to be compatible with VT1

Isoform 2 is the predominant form

It is a ligand for the NKG2-D type II integral membrane protein receptor

Microcephalin Polyclonal Antibody, 100ul Mammalian Expression Ran is active in itsThis gene encodes a DNA damage response protein. The encoded protein may play a role in G2 M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.