TRAP240 Polyclonal Antibody, 50ul[BT-AP09183] NGS Oligos Mutations in this gene result

Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy

The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells

which are 96% homologous

Upon activation of the alternative pathway

suggesting potential negative regulation through interference with complex formation via intramolecular binding

TRAP240 Polyclonal Antibody, 50ul[BT-AP09183] NGS Oligos Mutations in this gene resultMED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre initiation complex.