NFIP2 Polyclonal Antibody, 100ul Sampling Tubes Component C2 is a serum

Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system

Multiple transcript variants encoding different isoforms have been described

Colocalized with SLC3A2/4F2hc at the basolateral membrane of kidney cortex proximal tubules and small intestine epithelia of the villi

suggesting its involvement in c-Myc-mediated cell transformation

enhance T cell apoptosis induced by TCR/CD3 triggered activation

NFIP2 Polyclonal Antibody, 100ul Sampling Tubes Component C2 is a serumMay be involved in endocytosis. Regulates ENaC surface expression (By similarity). May be involved in NF kappa B and MAPK signaling pathways. induction: By T cell activation. PTM: Ubiquitinated by NEDD4 or NEDD4L; which does not affect turnover. subunit: Interacts with NEDD4L (By similarity). Interacts with NEDD4. tissue specificity: Expressed in brain lung heart skeletal muscle kidney liver and placenta.