HES-6 Polyclonal Antibody, 50ul Gene Synthesis This protein possesses intrinsic kinase

This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals

member RAS oncogene family encoded by RAB40B has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles

Notch 2 is cleaved in the trans-Golgi network

disease:Chromosomal aberrations involving FOXO1 are a cause of rhabdomyosarcoma 2 (RMS2)

The protein encoded by RREB1 (ras responsive element binding protein 1) is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters

HES-6 Polyclonal Antibody, 50ul Gene Synthesis This protein possesses intrinsic kinaseHES6 encodes a member of a subfamily of basic helix loop helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of HES6 family regulate cell differentiation in numerous cell types. Transcription cofactor HES 6 encoded by HES6 functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C terminus. Alternatively spliced transcript variants encoding different