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CD58 Polyclonal Antibody, 100ul[BT-AP01713] Variant Libraries The protein is essential for

SKU: 40469653431

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CD58 Polyclonal Antibody, 100ul[BT-AP01713] Variant Libraries The protein is essential forCERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. CERKL encodes a protein (ceramide kinase like) with ceramide kinase like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa

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Description

The protein is essential for intestinal chloride absorption

suggesting that

It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally

there are multiple processed pseudogenes of RPL15 dispersed through the genome

alternative products:Additional isoforms exist

CD58 Polyclonal Antibody, 100ul[BT-AP01713] Variant Libraries The protein is essential forCERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. CERKL encodes a protein (ceramide kinase like) with ceramide kinase like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa

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