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AIRE-1 Polyclonal Antibody, 100ul[BT-AP00312] Molecular Sciences ULK2 (unc-51 like autophagy activating

SKU: 40068636320

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AIRE-1 Polyclonal Antibody, 100ul[BT-AP00312] Molecular Sciences ULK2 (unc-51 like autophagy activatingAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with

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Description

ULK2 (unc-51 like autophagy activating kinase 2) encodes a protein that is similar to a serine/threonine kinase in C

while a related enzyme encoded by a different gene regulates fructose-2

which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains

and a charged cytoplasmic tail

2002 [PubMed 11784320])

AIRE-1 Polyclonal Antibody, 100ul[BT-AP00312] Molecular Sciences ULK2 (unc-51 like autophagy activatingAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with

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