mtTFA Polyclonal Antibody, 100ul Live Cell Imaging The encoded protein is present

The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles

Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress

and coagulation

Pseudogenes of this gene have been defined on chromosomes 1

and during mitosis

mtTFA Polyclonal Antibody, 100ul Live Cell Imaging The encoded protein is presentTFAM (transcription factor A, mitochondrial) encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in TFAM are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for TFAM on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants.