MAGC1 Polyclonal Antibody, 100ul Nucleic Acid Extraction Mutations in this gene impair

Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections

and thus suppresses apoptosis

NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily

May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF

Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity

MAGC1 Polyclonal Antibody, 100ul Nucleic Acid Extraction Mutations in this gene impairThis gene is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE homologous sequence, and therefore is about 800 aa longer than the other MAGE proteins.