RUFY1 Polyclonal Antibody, 100ul Cell Culture Flasks The RS domain is rich

The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors

The protease functions in the lysosome to cleave N-terminal tripeptides from substrates

is a 648 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain

PIAS4 also alters the nuclear localization

enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

RUFY1 Polyclonal Antibody, 100ul Cell Culture Flasks The RS domain is richRUFY1 (RUN and FYVE domain containing 1) encodes a protein that contains a RUN domain and a FYVE type zinc finger domain. The encoded protein binds to phosphatidylinositol 3 phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for RUFY1.