Shc(Phospho-Ser239/240) Rabbit Polyclonal Antibody, 20ul Immunology This protein possesses intrinsic kinase

This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals

Different family members and isoforms are thought to synthesize heparan sulfates with tissue-specific structures and functions

Differentially expressed in 56% of thyroid

The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al

the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL)

Shc(Phospho-Ser239/240) Rabbit Polyclonal Antibody, 20ul Immunology This protein possesses intrinsic kinaseThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike