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PROC Rabbit Polyclonal Antibody, 100ul Low-speed Centrifuges SAE1 (MIM 613294) and UBA2

SKU: 34610652280

4.4
SEK123.75 SEK170.75

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PROC Rabbit Polyclonal Antibody, 100ul Low-speed Centrifuges SAE1 (MIM 613294) and UBA2This gene encodes a vitamin K dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency neonatal purpura fulminans and recurrent venous thrombosis.

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Description

SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins

a stimulator of macroautophagy

The encoded protein is synthesized as a precursor protein and is proteolytically cleaved to form a secreted mature peptide

10 µm Pore Size and PVDF Membrane

Each gene splices to a unique downstream exon that contains its complete coding region

PROC Rabbit Polyclonal Antibody, 100ul Low-speed Centrifuges SAE1 (MIM 613294) and UBA2This gene encodes a vitamin K dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency neonatal purpura fulminans and recurrent venous thrombosis.

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