PJVK Rabbit Polyclonal Antibody, 20ul Polyclonal Antibody Preparation Aberrant expression of this gene

Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types

This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors

The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis

in humans| loss-of-function may play a role in tumorigenesis of gastrointestinal stromal tumors

endonuclease catalytic subunit encoded by ERCC4 forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair

PJVK Rabbit Polyclonal Antibody, 20ul Polyclonal Antibody Preparation Aberrant expression of this geneThe protein encoded by this gene is a member of the gasdermin family a family which is found only in vertebrates. The encoded protein is required for the proper function of auditory pathway neurons. Defects in this gene are a cause of non syndromic sensorineural deafness autosomal recessive type 59 (DFNB59).