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NSUN2 Rabbit Polyclonal Antibody, 50ul Cell Culture Plates Defects in this gene are

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NSUN2 Rabbit Polyclonal Antibody, 50ul Cell Culture Plates Defects in this gene areThis gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5 methylcytosine (m5C) at position 34 of intron containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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Description

Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49)

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NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al

NSUN2 Rabbit Polyclonal Antibody, 50ul Cell Culture Plates Defects in this gene areThis gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5 methylcytosine (m5C) at position 34 of intron containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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