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HRI Polyclonal Antibody, 100ul Peripheral Blood Separation Tube The encoded protein functions as

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HRI Polyclonal Antibody, 100ul Peripheral Blood Separation Tube The encoded protein functions asEukaryotic translation initiation factor 2 alpha kinase 1encoded by EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

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Description

The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal| or presequence| on protein cargo that is destined for the mitochondrial inner membrane and matrix

two G subunits plus the C

This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y

The activity of this receptor is mediated by G proteins which activate adenylyl cyclase

and proteolytic processing significantly affect the activity of this protein

HRI Polyclonal Antibody, 100ul Peripheral Blood Separation Tube The encoded protein functions asEukaryotic translation initiation factor 2 alpha kinase 1encoded by EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

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