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GGT2 Rabbit Polyclonal Antibody, 20ul ADME The cytogenetic location of this

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GGT2 Rabbit Polyclonal Antibody, 20ul ADME The cytogenetic location of thisGGT2 belongs to the gamma glutamyltransferase (GGT; EC 2. 3. 2. 2) gene family. GGT is a membrane bound extracellular enzyme that cleaves gamma glutamyl peptide bonds in glutathione and other peptides and transfers the gamma glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al. 2008

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Description

The cytogenetic location of this locus has been reported as both 8p11 and 8q11

Mutations in CLDN5 have been found in patients with velocardiofacial syndrome

are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal

Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function

Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4)

GGT2 Rabbit Polyclonal Antibody, 20ul ADME The cytogenetic location of thisGGT2 belongs to the gamma glutamyltransferase (GGT; EC 2. 3. 2. 2) gene family. GGT is a membrane bound extracellular enzyme that cleaves gamma glutamyl peptide bonds in glutathione and other peptides and transfers the gamma glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al. 2008

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