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B23 Monoclonal Antibody, 100ul[BT-MCA0200] NGS Oligos Mutations in this gene cause

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B23 Monoclonal Antibody, 100ul[BT-MCA0200] NGS Oligos Mutations in this gene causeThis gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been

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Description

Mutations in this gene cause X-linked agammaglobulinemia type 1| which is an immunodeficiency characterized by the failure to produce mature B lymphocytes| and associated with a failure of Ig heavy chain rearrangement

The mouse homolog of the protein encoded by CBLN4 competes with netrin to bind to the deleted in colorectal cancer receptor

This service has widespread applications in studying protein functional sites

Isoform 2 is testis specific

and higher expression of this gene may be correlated with shorter survival time in lung cancer patients

B23 Monoclonal Antibody, 100ul[BT-MCA0200] NGS Oligos Mutations in this gene causeThis gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been

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