SOX7 Polyclonal Antibody, 50ul Cellular Function Assays Alternate splicing of the gene

Alternate splicing of the gene results in several transcript variants encoding different isoforms

despite its location within a region of imprinted genes on chromosome 11

This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis

Increased expression of CASP2 may play a role in neurodegenerative disorders including Alzheimer's disease

Members of this family share a conserved motif termed

SOX7 Polyclonal Antibody, 50ul Cellular Function Assays Alternate splicing of the geneThis gene encodes a member of the SOX (SRY related HMG box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless type MMTV integration site family