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Krs-1/2 Polyclonal Antibody, 50ul RNA Synthesis and is involved in IL-31

SKU: 29469679722

4.2
SEK142.00 SEK178.00

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Krs-1/2 Polyclonal Antibody, 50ul RNA Synthesis and is involved in IL-31STK3 (serine threonine kinase 3) encodes a serine threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C terminal portion. The N terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants

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Description

and is involved in IL-31 signaling via activation of STAT-3 and STAT-5

Binds to and inhibits cyclin-dependent kinase activity| preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression

This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection

it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters

GATA binding protein 1 plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin

Krs-1/2 Polyclonal Antibody, 50ul RNA Synthesis and is involved in IL-31STK3 (serine threonine kinase 3) encodes a serine threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C terminal portion. The N terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants

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