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AFF4 Polyclonal Antibody, 100ul Hepatocytes It regulates muscle cell differentiation

SKU: 28226874398

4.0
PLN123.75 PLN168.75

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AFF4 Polyclonal Antibody, 100ul Hepatocytes It regulates muscle cell differentiationThe protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5; 11)(q31; q31q23).

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Description

It regulates muscle cell differentiation by inducing cell cycle arrest| a prerequisite for myogenic initiation

DNA damage response

This gene may also play a role in the stiff man syndrome

The FZD1 transcript is expressed in various tissues

ATP binding cassette subfamily B member 10 is a member of the MDR/TAP subfamily

AFF4 Polyclonal Antibody, 100ul Hepatocytes It regulates muscle cell differentiationThe protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5; 11)(q31; q31q23).

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