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KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation The protein encoded by LAIR2

SKU: 2768305829

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KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation The protein encoded by LAIR2This gene encodes a member of the TWIK related arachidonic acid stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia

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Description

The protein encoded by LAIR2 is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation

This cytokine is also found to promote proliferation and migration of endothelial cells

Mutations in this gene cause X-linked Charcot-Marie-Tooth disease

Although this gene has been referred to as RPL10

Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation

KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation The protein encoded by LAIR2This gene encodes a member of the TWIK related arachidonic acid stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia

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