PIGL Rabbit Polyclonal Antibody, 50ul Antibodies and selectively bind AU-rich elements

and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs

Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion

DUSP7 belongs to a class of DUSPs| designated MKPs| that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795)| JNK (see MIM 601158)| and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins

The protein encoded by this gene is a bifunctional

which play a role in myogenesis

PIGL Rabbit Polyclonal Antibody, 50ul Antibodies and selectively bind AU-rich elementsThis gene encodes an enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis which is the de N acetylation of N acetylglucosaminylphosphatidylinositol (GlcNAc PI). Study of a similar rat enzyme suggests that this protein localizes to the endoplasmic reticulum.