CBX2 Polyclonal Antibody, 100ul Cellular Function Assays C17 is a cytokine-like protein

C17 is a cytokine-like protein specifically expressed in bone marrow and cord blood mononuclear cells that bear the CD34 (MIM 142230) surface marker

and some types of T-cells

This gene encodes a protein initially identified as a thyroid-specific transcription factor

This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA

The protein encoded by this gene localizes to perinuclear endosomes

CBX2 Polyclonal Antibody, 100ul Cellular Function Assays C17 is a cytokine-like proteinCBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male to female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms