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SQSTM1/p62(Phospho-Ser403) Rabbit Polyclonal Antibody, 50ul Peptide Modification Mutations in AKT1 have been

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SQSTM1/p62(Phospho-Ser403) Rabbit Polyclonal Antibody, 50ul Peptide Modification Mutations in AKT1 have beenThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in

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Description

Mutations in AKT1 have been associated with the Proteus syndrome

and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins

Multiple transcript variants encoding different isoforms have been found for SMARCA4

The encoded protein (complement C6) is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis

MIM 601242)

SQSTM1/p62(Phospho-Ser403) Rabbit Polyclonal Antibody, 50ul Peptide Modification Mutations in AKT1 have beenThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in

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