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p53 Rabbit Polyclonal Antibody, 100ul[BT-AP11724] Pipette Controller Expression of this gene is

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p53 Rabbit Polyclonal Antibody, 100ul[BT-AP11724] Pipette Controller Expression of this gene isThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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Description

Expression of this gene is regulated by sterol regulatory element-binding proteins| transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids

The DNA repair protein complementing XP-A cells is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens

Perfect for risky experiments

Three transcript variants| one protein-coding and the other two non-protein coding| have been found for this gene

as a subunit of a heterodimeric complex

p53 Rabbit Polyclonal Antibody, 100ul[BT-AP11724] Pipette Controller Expression of this gene isThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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