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TM165 Rabbit Polyclonal Antibody, 50ul Cell Culture receptor-mediated endocytosis

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TM165 Rabbit Polyclonal Antibody, 50ul Cell Culture receptor-mediated endocytosisThis gene encodes a predicted transmembrane protein with a perinuclear Golgi like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants.

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Description

receptor-mediated endocytosis

Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546

This protein preferentially binds to the SH3 domain of c-Abl kinase

chondriotin sulfate

SLC22A18 is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15

TM165 Rabbit Polyclonal Antibody, 50ul Cell Culture receptor-mediated endocytosisThis gene encodes a predicted transmembrane protein with a perinuclear Golgi like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants.

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