Dok-2 Polyclonal Antibody, 100ul[BT-AP02698] Enzyme Activity Assays A mutation in this gene

A mutation in this gene results in trismus-pseudocamptodactyly syndrome

ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45

and expression of this gene may be a prognostic marker for several types of cancer

including itself

The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu

Dok-2 Polyclonal Antibody, 100ul[BT-AP02698] Enzyme Activity Assays A mutation in this geneThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.