Phospho-Abl1 (T735) Polyclonal Antibody, 50ul Drying & Desiccation a class of intracellular molecules

a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity

Variation in this gene has been associated with cerebellar ataxia

The protein encoded by this gene contains an atypical heat shock protein 70 (Hsp70) ATPase domain and is therefore a distant member of the mammalian Hsp70 family

a role in kidney and muscle development is indicated

Polymorphisms in this gene have been linked to breast and prostate cancer

Phospho-Abl1 (T735) Polyclonal Antibody, 50ul Drying & Desiccation a class of intracellular moleculesABL1 is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation, suggesting a