CNTP1 Polyclonal Antibody, 20ul Variant Libraries DNA repair protein XRCC1 encoded

DNA repair protein XRCC1 encoded by XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents

This protein has similarity to yeast Sec23p component of COPII

A structurally similar protein has been found in mouse

The encoded preproprotein (cathepsin D) is proteolytically processed to generate multiple protein products

and Pelger-Huet anomaly

CNTP1 Polyclonal Antibody, 20ul Variant Libraries DNA repair protein XRCC1 encodedThe gene product was initially identified as a 190 kD protein associated with the contactin PTPRZ1 complex. The 1,384 amino acid protein, also designated p190 or CASPR for 'contactin associated protein,' includes an extracellular domain with several putative protein protein interaction domains, a putative transmembrane domain, and a 74 amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a