Insulin R Polyclonal Antibody, 50ul[BT-AP04565] Cell Senescence NOL3 encodes an anti-apoptotic protein

NOL3 encodes an anti-apoptotic protein nucleolar protein 3 that has been shown to down-regulate the enzyme activities of caspase 2

Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly

not all variants have been fully characterized

can result in hypercalcemia and kidney stones

It has also been reported to be highly expressed in thyroids of patients with Graves disease

Insulin R Polyclonal Antibody, 50ul[BT-AP04565] Cell Senescence NOL3 encodes an anti-apoptotic proteinINSR encodes a member of the receptor tyrosine kinase family of proteins. Insulin receptor is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited