Phospho-Caspase-8 (S347) Polyclonal Antibody, 50ul Fluorescent Staining is an endogenous inhibitor of

is an endogenous inhibitor of the CXCR4 chemokine receptor

see MIM 114085

is a major intracellular protease

subcellular location:Localizes at endoplasmic reticulum exit sites

Mutations at this locus have been associated with microcephaly| seizures| and developmental delay

Phospho-Caspase-8 (S347) Polyclonal Antibody, 50ul Fluorescent Staining is an endogenous inhibitor ofCASP8 (caspase 8) encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the